Description
5-Amino-1MQ is a synthetic small molecule that acts as a potent, selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). By suppressing NNMT activity in adipose and metabolic tissues, it helps modulate cellular energy expenditure, shift lipid metabolism, and influence intracellular NAD+ pathways.
Key Characteristics & Mechanisms
- Target Enzyme: Selectively inhibits NNMT, an enzyme linked to metabolic slowdown and increased fat storage.
- Cellular Energy: Investigated for its role in altering intracellular cofactors like NAD+ and SAM, impacting mitochondrial function.
- Metabolic Studies: Evaluated in preclinical rodent models for reducing white adipose mass and body weight without suppressing food intake.
Specifications
- Formula: C₁₀H₁₁N₂⁺
- Purity: ≥ 98% - 99%
- Form: Lyophilized powder or encapsulated small molecule
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