Selank – 10mg

Selank

is a synthetic, heptapeptide analog of the naturally occurring immunomodulatory peptide tuftsin. It consists of the core tuftsin sequence (Thr-Lys-Pro-Arg) modified by the addition of three amino acids (Pro-Gly-Pro) at its C-terminus to significantly increase its metabolic stability and resistance to enzymatic degradation. Functioning as a potent, non-sedating anxiolytic and neuromodulator, Selank readily crosses the blood-brain barrier to influence central neurotransmitter systems, making it a cornerstone compound in neurochemical and behavioral research.

Key Features & Characteristics

• Mechanism of Action: Modulates the expression of the monoamine neurotransmitters (serotonin, dopamine, and norepinephrine) and increases the degradation of enkephalins.
• GABAergic Modulation: Enhances the binding affinity of GABA receptors without inducing the sedative, hypnotic, or muscle-relaxant properties typical of classic anxiolytics.
• Structural Stabilization: The proline-glycine-proline sequence extension protects the peptide chain from rapid peptidase breakdown, lengthening its active experimental window.
• Physical Form: Produced via high-fidelity chemical synthesis and provided as a stable, ultra-pure white lyophilized powder requiring laboratory reconstitution.

Primary Research Applications

• Anxiety & Stress Response Models: Extensively studied in animal behavioral assays to observe its capacity to suppress generalized anxiety, reduce fear responses, and lower emotional tension under stress.
• Cognitive Function & Memory: Investigated for its potential to improve learning capacity, enhance short-term memory consolidation, and support neuroplasticity during stress-induced cognitive deficits.
• Neuroimmunology & Inflammation: Evaluated for its ability to regulate systemic cytokine balances (such as IL-6 and IL-10), charting the complex physiological links between immune signaling and central nervous system health.

For Research Use Only. Not for human consumption, therapeutic, or diagnostic use